by S. Steiner, E. Horst, C.N. Johnson, E. Sprecher, L. Samuelov, E. O'Toole, G. Mehta, R. Iglesias Bartolome, P.A. Coulombe | Aug 1, 2026 | Berries, Cosmetics, Ingredients
The palmoplantar epidermis is distinct from other body sites, reflecting the mechanical strain it bears during locomotion. Pathogenic variants in over 50 genes are causative for palmoplantar epidermal differentiation disorders (pEDDs). One such disorder is KRT9-pEDD,...
by K. Fukuda, Y. Furuichi, R. Ozawa, T. Matsui, M. Amagai | Aug 1, 2026 | Berries, Cosmetics, Ingredients
The stratum corneum (SC), composed of dead keratinocytes (corneocytes), is vital for skin barrier function. We generated hairless mice expressing the ratiometric pH probe Venus–mCherry in the uppermost stratum granulosum cells (SG1 cells) and corneocytes (VmC mice),...
by E. Cohen, Y. Xu, S. Ghodke, A. Orosco, D. Wang, C.N. Johnson, M.K. Sarkar, J.E. Gudjonsson, L. Marchal, A. Hovnanian, C. Parent, P.A. Coulombe | Aug 1, 2026 | Berries, Cosmetics, Ingredients
The stress-induced keratin intermediate filament gene, KRT16, and K16 protein are spatially restricted to the suprabasal layers of the epidermis and widely used as biomarkers in psoriasis, hidradenitis suppurativa, atopic dermatitis, and other inflammatory disorders....
by E. Engels, J. Ryan Wolf, F. Tausk, M. Puelle | Aug 1, 2026 | Berries, Cosmetics, Ingredients
Psychodermatology utilizes both dermatology and psychiatry to provide treatment to patients that addresses interactions between the skin and the brain. This study sought to identify differences between psychodermatology(PD) and general dermatology(GD) patient...
by G. Ugwueke, N. Elbuluk | Aug 1, 2026 | Berries, Cosmetics, Ingredients
Melasma, post-inflammatory hyperpigmentation (PIH) and acquired dermal macular hyperpigmentation (ADMH) are pigmentary disorders that commonly affect skin of color individuals and may be associated with psychiatric burden. A retrospective chart review was conducted in...