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0556 Keratin 9 regulates YAP1 signaling in palmoplantar epidermis

The palmoplantar epidermis is distinct from other body sites, reflecting the mechanical strain it bears during locomotion. Pathogenic variants in over 50 genes are causative for palmoplantar epidermal differentiation disorders (pEDDs). One such disorder is KRT9-pEDD,...

0593 Keratin 16 spatially inhibits type I interferon responses in stressed and diseased skin

The stress-induced keratin intermediate filament gene, KRT16, and K16 protein are spatially restricted to the suprabasal layers of the epidermis and widely used as biomarkers in psoriasis, hidradenitis suppurativa, atopic dermatitis, and other inflammatory disorders....

0714 Exploring social determinants of health and demographic disparities between psychodermatology and general dermatology patient populations

Psychodermatology utilizes both dermatology and psychiatry to provide treatment to patients that addresses interactions between the skin and the brain. This study sought to identify differences between psychodermatology(PD) and general dermatology(GD) patient...